The effects of innovation and competition on drug prices
DOI:
https://doi.org/10.18381/eq.v23i1.7382Keywords:
Medicine prices; competition; innovation; price regulationAbstract
Objective: To analyze how innovation and competition affect the prices of specific medicine classes (cardiovascular, antibiotics, anti-inflammatory, and antidiabetes) across different Mexican cities, aiming to provide evidence for public policy design. Methodology: We employed a panel data regression analysis combined with a Principal Component Analysis (PCA) to identify the key variables driving price variation. Findings: Lagged innovation (measured by Google patent searches) and a higher number of firms are found to increase prices, while market concentration also drives them up. PCA identified the number of firms, population, and innovation as key contributing factors. Limitations: The study is restricted to urban cities in Mexico and four specific medicine classes, thus limiting the generalizability of the results. Originality: It provides recent empirical evidence on the nexus between competition, innovation, and prices, a topic scarcely explored within the Mexican context. Conclusions: Innovation and competition significantly impact medicine prices. Further studies are recommended to guide regulatory and promotional policies, including the measurement of deadweight loss generated by market imperfections.Downloads
References
Adams, C. P., & Brantner, V. V.. (2006). Estimating the cost of new drug development: is it really $802 million? Health Affairs, 25(2): 420-428. DOI: 10.1377/hlthaff.25.2.420
Alpert, A., Duggan, M., & Hellerstein. J. K. (2013). Perverse reverse price competition: average wholesale prices and Medicaid pharmaceutical spending. NBER Working Papers (w19367). DOI: 10.3386/w19367
Arreola Ornelas, H., Rosado Buzzo, A., García, L., Dorantes Aguilar, J., Contreras Hernández, I., & Mould Quevedo, J. F. (2012). Análisis de coste-efectividad en el tratamiento farmacológico del síndrome de fibromialgia en México. Reumatologia clinica, 8(3): 120- 127. DOI: 10.1016/j.reuma.2011.12.009
Ávalos-Ruvalcaba, T. M., Becerra-Verdin, E. M., Castañeda-Martínez, A., & FigueroaMorales, J. R. (2017). Implicaciones, acceso y costo de medicamentos en México. Paradigma económico pendiente. Atención Familiar, 24(2): 87-90. DOI: 10.22201/ facmed.14058871p.2017.2.59158
Bardey, D., Bommier, A., & Jullien, B. (2010). Retail price regulation and innovation: reference pricing in the pharmaceutical industry. Journal of Health Economics, 29(2): 303-316. DOI: 10.1016/j.jhealeco.2009.11.015
Bengtsson, M., & Sölvell, Ö. (2004). Climate of competition, clusters and innovative performance. Scandinavian Journal of Management, 20(3): 225-244. DOI: 10.1016/j. scaman.2004.06.003
Brekke, K. R., Königbauer, I., & Straume, O. R. (2007). Reference pricing of pharmaceuticals. Journal of Health Economics, 26(3): 613-642. DOI: 10.1016/j.jhealeco.2006.11.003
Collington, R., & Lazonick, W. (2022). Pricing for medicine innovation: a regulatory approach to support drug development and patient access. Institute for New Economic Thinking Working Paper Series, (176). DOI: 10.36687/ inetwp176
Cornaggia, J., Mao, Y., Tian, X., & Wolfe, B. (2014). Does banking competition affect innovation? Journal of Financial Economics, 115(1): 189- 209. DOI: 10.1016/j.jfineco.2014.09.001
Dumoulin, J. (2001). Global pricing strategies for innovative essential drugs. International Journal of Biotechnology, 3(3-4): 338-349. DOI: 10.1504/IJBT.2001.000169
Dunlop, W. C. N., Staufer, A., Levy, P., & Edwards, G. J. (2018). Innovative pharmaceutical pricing agreements in five European markets: a survey of stakeholder attitudes and experience. Health Policy, 122(5): 528- 532. DOI: 10.1016/j.healthpol.2018.02.008
Gandjour, A. (2013). Reference pricing and price negotiations for innovative new drugs: viable policies in the long term? PharmacoEconomics, 31(1): 11-14. DOI: 10.1007/s40273-012-0002- 9
García-Núñez, K. D., Sarmiento-Sánchez, E. S., Tapia, F., Venus, S., Cervantes-Sánchez, G., Cárdenas-Cárdenas, E. & HernándezMaldonado, E. (2024). Cost reduction for cancer drug treatment with a vial sharing strategy in a centralized preparation unit. Gaceta Mexicana de Oncología, 23(2): 79-83. DOI: 10.24875/j.gamo.23000055
Gilbert, R. J. (2006). Competition and innovation. Journal of Industrial Organization Education, 1(1): 1-23. DOI: 10.2202/1935-5041.1007
Gómez-Dantés, O., Wirtz, V. J., Reich, M. R., Terrazas, P., & Ortiz, M. (2012). A new entity for the negotiation of public procurement prices for patented medicines in Mexico. Bulletin of the World Health Organization, 90(10), 788-792. DOI: 10.2471/BLT.12.106633
Jayadev, A., & Stiglitz, J. (2009). Two ideas to increase innovation and reduce pharmaceutical costs and prices. Health Affairs, 28(1): w165-w168. DOI: 10.1377/ hlthaff.28.1.w165
Lexchin, J. (2004). The effect of generic competition on the price of brand-name drugs. Health Policy, 68(1): 47-54. DOI: 10.1016/j.healthpol.2003.07.007
Molina-Salazar, R. E., González-Marín, E., & Carbajal de Nova, C. (2008). Competencia y precios en el mercado farmacéutico mexicano. Salud Pública de México, 50(supl.): S496-S503. https://www.scielosp.org/pdf/spm/2008. v50suppl4/S496-S503/es
Rosado-Buzzo, A. y García-Mollinedo, M. L. (2019). Uso de medicamentos OTC: una alternativa para apoyar el Sistema Nacional de Salud de México. Salud y Administración, 6(17): 3-16. https://www.academia.edu/ dow nload/110001262/145-Tex to_del _ articulo-346-1-10-20190902.pdf
Sheridan, D., & Attridge, J. (2006). The impact of therapeutic reference pricing on innovation in cardiovascular medicine. Pharmacoeconomics, 24(supl.2): 35-54. DOI: 10.2165/00019053-200624002-00005
Stevens, H., & Huys, I. (2017). Innovative approaches to increase access to medicines in developing countries. Frontiers in Medicine, 4: 218. DOI: 10.3389/fmed.2017.00218
Symeonidis, G. (2019). Competition, innovation and the use of innovations. The Journal of Industrial Economics, 67(3-4): 565-592. DOI: 10.1111/joie.12209 Tang, J. (2006). Competition and innovation behaviour. Research Policy, 35(1): 68–82. DOI: 10.1016/j.respol.2005.08.004
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Moisés Alejandro Alarcón Osuna

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.